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L-Arbutin

L-arbutin (also referred to simply as arbutin), naturally occurs in a variety of plants. Most commonly, it is extracted from the bearberry plant, which has been used in herbal medicine as far back as the 13th century. Bearberry was listed in the London Pharmacopoeia in 1788 and is often referred to using its Latin name, uva ursi. L-arbutin is also found in wheat, cranberries, blueberries, and the skins of pears.

When applied to the skin, L-arbutin inhibits the action of the enzyme tyrosinase, which is the precursor to melanin. Melanin is the pigment that forms when human skin is exposed to UVB radiation, primarily from the sun. The darkening of the skin caused by the release of melanin is commonly referred to as a sun tan. The body releases melanin in response to the action of UVB radiation on the skin because melanin is a photoprotectant. Melanin absorbs harmful UV rays and converts them into harmless heat. Melanin is responsible for protecting the skin from DNA damage that is the root cause of skin cancers, such as malignant melanoma.

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Although the action of melanin is generally beneficial, some individuals produce melanin unevenly. People with fair skin can find that melanin is concentrated in localized areas of the skin, causing freckles and moles. As skin ages, excessive sun exposure can result in clumping of melanin in the form of age spots. The skin condition known as chloasma or melasma is the result of over-stimulation of the melanocytes that produce melanin pigment. Dark, hyperpigmented areas form on the surface of the skin, most commonly on the cheeks, lips, nose, and forehead.

Individuals who are self-conscious about hyperpigmentation may turn to skin lighteners, such as L-arbutin and hydroquinone. Hydroquinone has been the subject of debate in many countries. Clinical tests on hydroquinone have revealed some serious side effects, including ochronosis, skin irritation, and skin cancer. These test results have led to hydroquinone being banned in Japan and the European Union. The U.S. Food and Drug Administration (FDA) have classified hydroquinone as safe for topical use. However, some individuals may prefer to avoid using hydroquinone, given the negative test results.

L-arbutin is considered a useful ingredient in anti-aging skin creams, lotions and serums.

L-arbutin is a glycosylated hydroquinone. It produces very similar effects to hydroquinone in terms of blocking the production of melanin. However, clinical tests have revealed that L-arbutin appears to have a gentler action, meaning that it is less likely to cause skin irritation. In addition, L-arbutin is non-systemic, which means that it does not penetrate the skin and enter the bloodstream. This suggests that L-arbutin does not have the same potential for toxic side effects as hydroquinone. However, care should be taken not to use L-arbutin excessively as some studies have suggested that long-term use of L-arbutin may have negative health implications.

L-arbutin is considered a useful ingredient in anti-aging skin creams, lotions and serums. The reason for this is that L-arbutin addresses the discolored areas of the skin known as age spots. These hyperpigmented areas of the skin are a visible sign of the premature aging effects of the harmful UVA and UVB rays that radiate from the sun. Sun exposure is unavoidable. Even on overcast days, powerful UVA and UVB rays emanating from the sun reach the earth’s surface. For this reason, it is essential to wear a high factor sunscreen every day to protect the skin from sun damage.

L-arbutin is currently the only chirally-correct skin lightener on the market.

L-arbutin is currently the only chirally-correct skin lightener on the market. Molecules exist in two forms, which are mirror images of each other. The body will recognize one version of the molecule and use it as intended. Meanwhile, the molecule that is the mirror image is not recognized by the body. At best, the body disposes of the mirror image molecule as waste. At worst, the body may regard it as a toxin, leading to irritation, inflammation, and free radical damage.

The leaves of the bearberry plant, which contain L-arbutin, were traditionally harvested, dried, and ingested as a remedy for bladder and urinary tract infections. L-arbutin has an antibacterial action, which contributes to this healing effect. Dried, powered bearberry plant leaves, known as uva ursi, can be taken in capsule form. Alternatively, the capsules can be broken open and made in to a hot, herbal infusion. Care should be taken to follow dosage guidelines as excessively high levels of uva ursi can cause liver damage.

  

L-Arbutin Products

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Intensive spot treatment features triple strength actives to tackle stubborn brown spots on the face, body and hands with safe, natural, clinically proven ingredients.
$62.00
0.5oz | OS075
In Stock
 
An advanced lightening formula to diminish discoloration and improve overall skin health.
$80.00
1oz | SK036
In Stock
 
This serum offers soothing relief for conditions such as rosacea and dermatitis.
$135.00
1oz | IS008
In Stock
 
This super serum reduces the signs of aging while lightening discolorations.
$140.00
1oz | IS007
In Stock
A topical non-prescription formula with a non-hydroquinone skin brightener.
$92.00
2oz | OB091
In Stock
 
A topical non-prescription formula with a non-hydroquinone skin brightener containing arbutin, exfoliants, and antioxidants.
$88.00
2oz | OB092
In Stock
 
A topical cream formulated with arbutin and Vitamins C & E to help rejuvenate.
$92.00
2oz | OB096
In Stock
 
A multi-tasking, oil and fragrance free lightening treatment that delivers glowing results.
$80.00
1oz | GO041
In Stock
Helps to even out skin tone and erase dark spots.
$65.00
1.7oz | YD011
In Stock
 
An all-over treatment that helps to fade sun damage, dark spots and acne scarring.
$88.00
1oz | DG147
In Stock
 
Diminish lines, wrinkles and hyperpigmentation with this fast-acting serum.
$128.00
1oz | IS003
In Stock
 
Address all of the physical factors that represent upper lip aging.
$38.00
0.5oz | DT009
In Stock
A powerful corrective serum that lightens and brightens skin.
$35.00
1.17oz | RC039
In Stock
 
Restore the youthful appearance to your hands with this treatment.
$22.00
4oz | DT025
In Stock
 
Even out skin tone and reduce any discoloration with this oil-free serum
$50.95
0.5oz | KI032
In Stock
 
Smoothes fine lines, reduces puffiness, firms & tightens while brightening the eye area.
$68.00
0.5oz | DG152
In Stock
A powerful anti-aging lightening treatment formulated target discoloration and hyperpigmentation.
$120.00
1 oz | IS045
In Stock
 
Diminish lines, wrinkles and hyperpigmentation with this fast-acting serum.
$78.00
0.5oz | IS004
In Stock
 
Purify and brighten skin with this chemical and physical exfoliator.
$42.00
6.7oz | GH006
In Stock
 
Reduces brown spots, age spots, sun spots and other skin discolorations including dark circles under eyes.
$85.00
2 oz | MC008
In Stock
Provides a safe and effective at-home alternative to in-office laser removal.
$38.00
0.11oz | MF090
In Stock
 
An elegant, nourishing cream that addresses the common signs of aging around the eyes.
$30.00
0.5oz | FC009
In Stock
 
A fast-acting formula that pinpoints and fades stubborn dark spots and discolorations.
$52.00
0.3oz | IE095
In Stock
 
Targets uneven skin tone, skin discoloration and age spots.
$49.00
1oz | DT006
In Stock
A potent, effective lightener.
$51.00
0.5oz | EM009
In Stock
 
A fast absorbing serum that is clinically proven to lighten darkened skin discolorations.
$34.00
.5 oz | SG003
In Stock
 
An exfoliating cleanser that removes makeup, excess oils, grime and toxins.
$36.00
6.7oz | TP065
In Stock
 
This anti-aging hand treatment works to restore the youthful appearance to your hands
$14.00
1.7oz | DT036
In Stock
Visibly lightens discoloration, uneven skin tone & brown spots
$68.00
1.7oz | OS076
In Stock
 
This treatment diminishes sun damage, wrinkles and hyperpigmentation.
$95.00
1oz | JM167
In Stock
 
For skin rejuvination at the cellular level.
$105.00
1.17oz | RC080
In Stock
 
For powerful skin lightening and brightening without a prescription.
$48.00
0.5oz | CQ011
In Stock
Unique emulsion delivers your skin's daily dose of Vitamin D.
$65.00
1oz | DG141
In Stock
 
This treatment helps skin recover from sun damage while preventing dark spots and wrinkles.
$105.00
1.7oz | KK011
In Stock
 
Transform your skin while you sleep for a softer, smoother, younger-looking complexion.
$90.00
1oz | KS077
In Stock
 
This brightener reduces the appearance of dark spots on the face and hands.
$58.00
1oz | QS015
In Stock
A treatment that reduces lines and wrinkles while promoting collagen synthesis.
$120.00
1.35oz | DU012
In Stock
 
Reduces neck creases, sun damage and improves skin texture.
$61.00
1.5oz | IE069
In Stock
 
The ultimate multi-tasking face cream formulated to help prevent and combat aging.
$38.00
1.7oz | FC006
In Stock
 
A rich, multi-action moisturizer that provides deep hydration and anti-aging benefits.
$36.00
1.7oz | FC007
In Stock
Enjoy younger-looking skin from head to toe.
$161.00
1.7oz | MC031
In Stock
 
Enjoy younger-looking skin from head to toe.
$249.00
3.5oz | MC029
In Stock
 
A skin clarifying and brightening complex that makes skin look brighter.
$95.00
1oz | LJ016
In Stock
 
Protect and repair the damaging effects of the sun.
$162.00 $185.00 value
MCPK010
In Stock
An antioxidant serum formulated with 10% L-ascorbic acid and 4% arbutin to help protect skin and to minimize future skin damage.
$112.00
1oz | OB095
In Stock
 
Reveal radiance and clarity in the first application.
$45.00
0.5oz | DT007
No Longer Available
 
A fast absorbing serum that is clinically proven to lighten darkened skin discolorations.
$64.00
1 oz | SG004
Out of Stock
 
Corrects the skin's moisture balance, absorbency and tone.
REG $55.00  NOW $33.00
0.5oz | DT010
No Longer Available
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