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Allantoin

Allantoin is a compound found in the urine of most mammals with the exception of human and primates. Mammals other than humans and primates convert uric acid, a chemical produced when purines are broken down, to allantoin, which is then excreted through the urine. Humans and primates lack the enzyme that converts uric acid to allantoin, so uric acid is excreted instead. When uric acid isn’t eliminated quickly enough through the kidneys, it builds up in the bloodstream. This can lead to a common condition called gout. Allantoin can also be extracted from the comfrey plant, an herbal plant known for its medicinal benefits or produced synthetically by oxidizing purines.

Like the comfrey plant, allantoin is recognized by herbalists as having medicinal value. Herbalists use it to treat psoriasis, a chronic skin condition characterized by inflammation and reddened patches of skin with silvery scales. It may be effective for treating other skin conditions as well. One study showed that a topical cream containing allantoin was effective for treating itching associated with atopic dermatitis. This isn’t surprising since allantoin has anti-inflammatory properties and the ability to ease skin irritation. It also acts as an emollient, helping to soften skin and smooth dry, irritated skin.

Creams and ointments containing allantoin are used to treat skin conditions like diaper rash in babies, wind burned skin from exposure to cold, sunburned skin from overexposure to the sun, chapped lips and to ease the discomfort of cold sores. Allantoin can also be applied to scrapes, burns and cuts as a way to soothe and protect the area. It also appears to speed up wound healing by stimulating new skin cell growth and is sometimes used to treat radiation skin burns in people who are undergoing radiation treatment for cancer. Allantoin is available as a shampoo combined with coal tar to treat scalp psoriasis, seboorhea, dandruff and eczema involving the scalp.

Allantoin not only reduces skin irritation, it also moisturizers and improves the texture of skin.

Because of its anti-inflammatory properties and its ability to soothe skin irritation, allantoin is an ingredient in some cosmetic and personal care products. In skin care products, allantoin helps to moisturize and soften skin and acts as a keratinolytic. Keratinolytics soften keratin, a tough, inflexible protein found in the outer layer of the skin called the epidermis. By softening keratin, allantoin allows skin to hold onto water better. This makes it moister, softer and better hydrated. Keratinolytics also dissolve the material that holds skin cells together. This enables the outermost layer of skin cells to shed or slough off more easily, creating a smoother skin surface. Allantoin not only reduces skin irritation, it also moisturizers and improves the texture of skin.

A wide range of cosmetic, skin and personal care products contain allantoin as an ingredient. These include sunscreens, lip balm, lipsticks, moisturizers, body lotions, eye creams, toothpaste, mouthwash, acne treatments, toners, hand creams, shaving cream, bath products, baby powders and hair gels. These products usually contain allantoin concentrations between 0.5% to 2.0% percent.

Allantoin appears to be safe for skin and for overall health.

Is it Safe? Allantoin appears to be safe in the amounts added to cosmetic, skin and personal care products. The Environmental Working Group Skin Deep database classifies it as a low hazard cosmetic ingredient. It has not been linked with health problems and doesn’t accumulate in the environment. It’s also unlikely to cause allergic reactions or skin problems due to its anti-inflammatory properties and its ability to soothe skin irritation. Allantoin appears to be safe for skin and for overall health.

Although allantoin is safe when used topically, allantoin and extracts from the comfrey plant shouldn’t be used orally since they can cause liver damage. At one time, comfrey was used to treat digestive problems until it was discovered the plant contains pyrrolizidine alkaloids that are liver toxic.

In summary, Allantoin is a safe cosmetic ingredient when used topically in the amounts found in cosmetic and personal care products. It has emollient properties that help skin retain moisture, and it reduces skin irritation from a variety of causes. Because it’s a keratolytic, it can improve skin texture, making it feel smoother and reflect light better. It may also be beneficial for treating some skin conditions including psoriasis and eczema.

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Allantoin Products

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A mix-to-activate, duo-phase mask to quench your thirsty skin.
$75.00
4 ct | ER056
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Includes the microcurrent facial toning device and an attachment for lip and eye area.
$429.00 $503.00 value
NF041
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Limited-edition value set includes a full size Lifter Vitamin C and Hyaluronic Acid Serum S3.
$199.00 $283.00 value
1 ct | NF035
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Improve the appearance of your scars and SAVE!
$87.00 $96.00 value
5.28 oz | MEPK01
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Moisture replenisher with vitamin-E and marine extracts.
$60.00
2 oz | SK015
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Clear away oil, dirt, and sweat 6x better than hands while prepping face and neck for a smoother, closer shave.
$189.00
1 ct | CS196
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Improves moisture retention and alleviates dryness and irritation.
$75.00
1.7 oz | OS053
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A nemesis of breakouts, these clarifying pads help remove impurities and excess oil from your skin.
$32.00
50 ct | DQ072
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Helps to even out skin tone and erase dark spots.
$65.00
1.7 oz | YD011
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Brighten, smooth, soften and literally 'polish' the complexion to a healthy pink glow.
$68.00
1.06 oz | CL047
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An ultra-rich, antioxidant moisturizer that soothes, heals and repairs skin.
$110.00
1.7 oz | ER036
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Formulated for sensitive or traumatized skin.
$34.00
8 oz | SK022
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Limited Time Offer! Purchase the RapidLash Eyelash Enhancing Serum
$89.00 $100.00 value
0.2 oz | RPPK01
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A healing, soothing and desensitizing cream for Rosacea and sensitive skin.
$83.50
1.7 oz | PE038
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Provides deep hydration and improves the appearance of signs of photo-aging.
$86.70
1.7 oz | OB080
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Regular use will help increase the elasticity and resilience of the skin to greatly reduce the appearance of loose, sagging skin.
$160.00
2 oz | CL044
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The skin clarifying, anti-aging concentrate that deeply cleanses and gently exfoliates.
$65.00
1.7 oz | TM002
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A non-drying, clarifying toner that reduces excess oil and enlarged pores.
$45.00
6 oz | NV139
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Promotes firmer, healthier, younger looking skin.
$85.00
1.7 oz | OS036
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Eliminate fine lines and wrinkles with this unique anti-aging wrinkle cure concentrate.
$129.95
4 oz | JE001
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Helps prevent premature aging while restoring moisture and smoothing the lips.
$38.00
0.33 oz | SK014
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A very nourishing moisturizer that stimulates cellular renewal.
$90.00
1.7 oz | MI004
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Rapidly restores skin's moisture.
$65.55
2 oz | SM066
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Luxuriously rich moisturizers instantly make the driest skin feel moist and velvety.
$75.00
2 oz | CL027
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A rich and light eye cream that softens and smoothes the eye area.
$67.50
1 oz | PE019
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Immediately produces supple, moist skin texture.
$59.00
2 oz | CL028
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A richly textured, regenerating cream for those with maturing skin.
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1 oz | TE004
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Lift and tone aging and sagging skin, while reducing skin discoloration.
$84.00
1 oz | NF016
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Restores and maintains a healthy skin barrier.
$125.00
1.7 oz | OS054
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A unique treatment pad that tightens, tones and stimulates for radiant skin.
$80.00
60 ct | NV240
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This treatment diminishes sun damage, wrinkles and hyperpigmentation.
$95.00
1 oz | JM167
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Gentle chemical exfoliating age management treatment.
$68.00
1 oz | CQ007
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Gentle, oil-free gel mask deeply hydrates for visibly brighter, plumper, more radiant skin.
$80.00
1.67 oz | TM009
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This deep-hydrating booster refreshes, plumps and softens skin.
$90.00
1 oz | ER033
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Unique blend of gentle acids and trans-retinol.
$77.00
1 oz | CQ006
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Repair, restore and protect your skin with this anti-aging serum.
$140.00
1.7 oz | ER041
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A bio-cellulose sheet mask formulated to smooth and tighten the neck area with synthetic snake venom.
$65.00
8 ct | RD144
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Contains 10% vitamin C in a scientifically formulated combination of hydrolized and free-form ascorbic acid.
$110.00
1 oz | CL045
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This powerhouse cream brightens skin tone and redefines the facial contour.
$86.00
1.7 oz | PE137
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Erase Stubborn & Hard-To-Remove Wrinkles.
$129.95
1 oz | JE008
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The ideal skin prep product that promotes the effectiveness and absorption of all serums and moisturizers.
$88.00
1 oz | NF014
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A concentrated peptide complex strengthens skin from within by increasing microcirculation and relaxing facial muscles to inhibit wrinkles.
$84.00
1 oz | NF015
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Noticeably reduce the look of fine lines and wrinkles.
$63.00
1 oz | CL017
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Stimulate new skin cells to the surface.
$72.00
2 oz | CL032
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This kit helps to reduce the symptoms associated with Keratosis Pilaris.
$68.00 $70.00 value
GT040
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Hydroxy acids stimulate the skin's normal sloughing action to reveal a smooth, fresh complexion.
$35.00
6 oz | CL030
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Helps to renew and rejuvenate the skins firmness and resilience.
$75.00
1.17 oz | RC102
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Enjoy the benefits of a chemical peel and gentle microdermasion in one product.
$75.00
1.7 oz | QB022
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