Skin Care Best Sellers
465 results
Best known for our skincare, we've spent over 20 years curating effective skincare that protects, prevents and corrects the visible signs of aging, hyperpigmentation, dark circles and more. Muse over skincare that has been tried, tested and rated 5* by you, our customers. Suitable for myriad skin types, lifestyle or concerns, our 5* products will inspire your skincare journey.
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Log in/sign up to use Wishlists!Sunday Riley Good Genes All-In-One Lactic Acid Treatment 1.7oz
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$122.00 -
Log in/sign up to use Wishlists!iS Clinical Cleansing Complex (6 oz.)
15% off at Dermstore with code: WELCOME15
Start your Dermstore journey with 15% off* your first order at Dermstore using code WELCOME15. *Offer valid for first time customers only. Cannot be combined with other discounts. Valid on participating products below only.SHOP AT DERMSTORE$48.00 -
Log in/sign up to use Wishlists!SkinCeuticals Refine and Hydrate Anti-Aging Essentials Regimen with Vitamin C and Hyaluronic Acid
Earn 5% back at Dermstore
Become a Dermstore Rewards Member & earn 5% back every time you shop. That means you earn 5 points for every $1 you spend on ANY product, good towards any future purchase. To redeem this offer, opt into the reward program via your Dermstore account page & start earning today.JOIN NOW AT DERMSTORE$272.00 -
Log in/sign up to use Wishlists!Elemis Pro-Collagen Cleansing Balm 100g
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$69.00 -
Log in/sign up to use Wishlists!SkinMedica TNS Recovery Complex 1 oz (Worth $285)
15% off at Dermstore with code: WELCOME15
Start your Dermstore journey with 15% off* your first order at Dermstore using code WELCOME15. *Offer valid for first time customers only. Cannot be combined with other discounts. Valid on participating products below only.SHOP AT DERMSTORE$230.00 -
Log in/sign up to use Wishlists!Embryolisse Lait Creme Concentre Moisturizer 2.54 fl oz
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$29.00 -
Log in/sign up to use Wishlists!Obagi Medical Hydrate Luxe (1.7 oz.)
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$78.00 -
Log in/sign up to use Wishlists!SkinCeuticals Phyto A+ Brightening Treatment Lightweight Moisturizer 1 fl. oz
Double Points at Dermstore
Earn double points at Dermstore's Black Friday Sale by becoming a Dermstore Rewards member. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Sign up for free by opting in on the account page. Participating products only. Black Friday Sale ends 12/2/24 at 11:59 p.m. PT.EARN AT DERMSTORE$110.00 -
Log in/sign up to use Wishlists!BIOEFFECT EGF Plumping and Firming Serum 15ml
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$175.00 -
Log in/sign up to use Wishlists!COSRX Advanced Snail 96 Mucin Power Essence 100ml
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$25.00 -
Log in/sign up to use Wishlists!Avène Thermal Spring Water (10.1 oz.)
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$19.00 -
Log in/sign up to use Wishlists!Epionce Renewal Facial Cream
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$102.00 -
Log in/sign up to use Wishlists!Lancer Skincare The Method: Polish (120g)
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$80.00 -
Log in/sign up to use Wishlists!SkinCeuticals MicroExfoliating Cleanser 150ml
Double Points at Dermstore
Earn double points at Dermstore's Black Friday Sale by becoming a Dermstore Rewards member. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Sign up for free by opting in on the account page. Participating products only. Black Friday Sale ends 12/2/24 at 11:59 p.m. PT.EARN AT DERMSTORE$35.00 -
Log in/sign up to use Wishlists!Medik8 C-Tetra Serum 30ml
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$49.00 -
Log in/sign up to use Wishlists!Medik8 Crystal Retinal 1 Serum 30ml
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$54.00 -
Log in/sign up to use Wishlists!Dr Dennis Gross Advanced Retinol + Ferulic Overnight Wrinkle Treatment
15% off at Dermstore with code: WELCOME15
Start your Dermstore journey with 15% off* your first order at Dermstore using code WELCOME15. *Offer valid for first time customers only. Cannot be combined with other discounts. Valid on participating products below only.SHOP AT DERMSTORE$87.00 -
Log in/sign up to use Wishlists!Peter Thomas Roth Water Drench Broad Spectrum SPF45 Hyaluronic Cloud Moisturizer 1.7 fl. oz
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$55.00 -
Log in/sign up to use Wishlists!ALGENIST Triple Algae Eye Renewal Balm 15ml
15% off at Dermstore with code: WELCOME15
Start your Dermstore journey with 15% off* your first order at Dermstore using code WELCOME15. *Offer valid for first time customers only. Cannot be combined with other discounts. Valid on participating products below only.SHOP AT DERMSTORE$68.00 -
Log in/sign up to use Wishlists!PCA SKIN Hydrator Plus Broad Spectrum SPF 30 1.7 oz
Earn 5% back at Dermstore
Become a Dermstore Rewards Member & earn 5% back every time you shop. That means you earn 5 points for every $1 you spend on ANY product, good towards any future purchase. To redeem this offer, opt into the reward program via your Dermstore account page & start earning today.JOIN NOW AT DERMSTORE$48.00 -
Log in/sign up to use Wishlists!La Roche-Posay Anthelios Melt-in Milk Body and Face Sunscreen Lotion Broad Spectrum SPF 100 (Various Sizes)
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$26.99 -
Log in/sign up to use Wishlists!Natura Bissé Inhibit Tensolift Neck Cream 50ml
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$235.00 -
Log in/sign up to use Wishlists!Avène Cicalfate+ Restorative Protective Cream (3.3 oz.)
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$42.00 -
Log in/sign up to use Wishlists!First Aid Beauty Ultra Repair Face Moisturizer (1.7 oz.)
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$28.00 -
Log in/sign up to use Wishlists!Elemis Pro-Collagen Night Cream 50ml
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$170.00 -
Log in/sign up to use Wishlists!PCA SKIN Intensive Age Refining Treatment 0.5 Percent Pure Retinol Night
Earn 5% back at Dermstore
Become a Dermstore Rewards Member & earn 5% back every time you shop. That means you earn 5 points for every $1 you spend on ANY product, good towards any future purchase. To redeem this offer, opt into the reward program via your Dermstore account page & start earning today.JOIN NOW AT DERMSTORE$118.00 -
Log in/sign up to use Wishlists!Dermalogica Precleanse (150ml)
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$49.00 -
Log in/sign up to use Wishlists!SENTÉ Dermal Repair Cream (1.7 oz.)
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$164.00 -
Log in/sign up to use Wishlists!U Beauty The Super Hydrator 1.7 fl oz
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$168.00 -
Log in/sign up to use Wishlists!MDSolarSciences Hydrating Sheer Lip Balm SPF30 0.15 oz (Various Shades)
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$25.00 -
Log in/sign up to use Wishlists!DHC Silky Cotton Cosmetic Pads (80 Pack)
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$6.00 -
Log in/sign up to use Wishlists!Elta MD Foaming Facial Cleanser Duo (Worth $64.00)
Earn 5% back at Dermstore
Become a Dermstore Rewards Member & earn 5% back every time you shop. That means you earn 5 points for every $1 you spend on ANY product, good towards any future purchase. To redeem this offer, opt into the reward program via your Dermstore account page & start earning today.JOIN NOW AT DERMSTORE$58.00 -
Log in/sign up to use Wishlists!Medik8 Advanced Night Ceramide Cream 48g
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$76.00 -
Log in/sign up to use Wishlists!Epionce Gentle Foaming Cleanser
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$36.00 -
Log in/sign up to use Wishlists!DHC Super Collagen Supreme 50ml
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$31.00 -
Log in/sign up to use Wishlists!Lancer Skincare The Method: Polish (Bonus Size 227g, Worth $142)
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$120.00 -
Log in/sign up to use Wishlists!Perricone MD Hypo Nourishing Moisturizer 2oz FG
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$75.00 -
Log in/sign up to use Wishlists!iS Clinical SHEALD Recovery Balm (2 oz.)
15% off at Dermstore with code: WELCOME15
Start your Dermstore journey with 15% off* your first order at Dermstore using code WELCOME15. *Offer valid for first time customers only. Cannot be combined with other discounts. Valid on participating products below only.SHOP AT DERMSTORE$79.00 -
Log in/sign up to use Wishlists!Medik8 Liquid Peptides Serum 30ml
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$64.00 -
Log in/sign up to use Wishlists!Colorescience Sunforgettable Total Protection Color Balm 0.32oz. (Various Shades)
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$39.00 -
Log in/sign up to use Wishlists!SkinCeuticals Phyto Corrective Mask 60ml
Double Points at Dermstore
Earn double points at Dermstore's Black Friday Sale by becoming a Dermstore Rewards member. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Sign up for free by opting in on the account page. Participating products only. Black Friday Sale ends 12/2/24 at 11:59 p.m. PT.EARN AT DERMSTORE$70.00 -
Log in/sign up to use Wishlists!ESPA Pink Pomelo Lip Balm 10g
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$28.00 -
Log in/sign up to use Wishlists!Obagi Clinical Kinetin+ Exfoliating Cleansing Gel 5.1 fl. oz
Obagi Clinical Dark Spot Disruptor Discoloration Correcting Serum Deluxe Sample 5ml (Worth $11.00) Worth $11.00$11 Obagi Clinical Gift
Receive an Obagi Clinical Dark Spot Disruptor Discoloration Correcting Serum Deluxe Sample 5ml (Worth $11) when you spend $100 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.SHOP NOW$39.00 -
Log in/sign up to use Wishlists!Epionce Purifying Wash 8oz
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$46.00 -
Log in/sign up to use Wishlists!Alchimie Forever Kantic Brightening Moisture Mask
Double Points at Dermstore
Earn double points at Dermstore's Black Friday Sale by becoming a Dermstore Rewards member. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Sign up for free by opting in on the account page. Participating products only. Black Friday Sale ends 12/2/24 at 11:59 p.m. PT.EARN AT DERMSTORE$60.00 -
Log in/sign up to use Wishlists!Replenix BP Acne Gel 10% Spot Treatment
Up to 30% off at Dermstore
Receive up to 30% off at Dermstore's Black Friday Sale on select brands. Participating products only. Black Friday Sale ends 12/2/2024 at 11:59 p.m. PST.SHOP AT DERMSTORE$34.00 -
Log in/sign up to use Wishlists!IMAGE Skincare ORMEDIC Balancing Facial Cleanser 6 fl. oz
Double Points at Dermstore
Earn double points at Dermstore's Black Friday Sale by becoming a Dermstore Rewards member. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Sign up for free by opting in on the account page. Participating products only. Black Friday Sale ends 12/2/24 at 11:59 p.m. PT.EARN AT DERMSTORE$39.00 -
Log in/sign up to use Wishlists!Hero Cosmetics Rescue Balm Post-Blemish Recovery Cream
Double Points at Dermstore
Earn double points at Dermstore's Black Friday Sale by becoming a Dermstore Rewards member. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Sign up for free by opting in on the account page. Participating products only. Black Friday Sale ends 12/2/24 at 11:59 p.m. PT.EARN AT DERMSTORE$12.99